?SYNTHESIS OF NEW BENZOTHIAZOLE-2-ACRYLIC ACID DERIVATIVES

Authors

  • EMAD M.M. KASSEM Department of Medicinal Chemistry, National Research Centre,Dokki, Cairo, Egypt
  • JOSEPHINE M. MICHAEL Department of Medicinal Chemistry, National Research Centre,Dokki, Cairo, Egypt
  • A.H.EL- MASRY Department of Medicinal Chemistry, National Research Centre,Dokki, Cairo, Egypt

Keywords:

Maleic anhydride, O-aminothiophenol, Benzothiazole-2-acrylic acid.

Abstract

Benthothiazole-2-acrylic acid IV reacted with thiourea to give the thiazole derivative V which reacted with
different aldehydes to give compounds of the type VI.Also, compound IV reacted with some sulfa drugs and some
amines to give amide derivatives of the type VII and IX. respectively. The prepared compounds showed potential
antimicrobial activity.

Published

1995-12-18

Issue

Vol. 38 No. 11-12 (1995): Pakistan Journal of Scientific and Industrial Research

Section

Articles

How to Cite

?SYNTHESIS OF NEW BENZOTHIAZOLE-2-ACRYLIC ACID DERIVATIVES. (1995). Biological Sciences - PJSIR, 38(11-12), 424-427. https://www.v2.pjsir.org/index.php/biological-sciences/article/view/2539